Tuesday, February 26, 2013

Don't blame Jeff

In case you weren?t around yesterday Marlins owner Jeff Loria published a full page ?Letter to our fans? in the Miami papers, purporting to explain the Marlins? controversial and exceedingly unpopular moves since last year. The full text of it can be seen at our post on it yesterday.

I just got a chance to read it and noticed something. Despite saying ?the buck stops with me? and ?I take my share of the blame where it?s due,? he is pretty clear in his letter that the buck hasn?t gotten to him yet and that any blame to him is not due. Indeed,?Loria believes that he is in no way to blame for the state of the Marlins and the fans? unhappiness with the franchise.

Here is a list of the people Loria believes to be responsible for where things currently stand, in order as they are mentioned in the letter:

  • Anyone who does not believe the trade with the Blue Jays was a good idea because it was ?universally celebrated by baseball experts outside of Miami for its value.?
  • Every member of last year?s roster, all of which Loria says ?underperformed as compared to their career numbers.?
  • ?naysayers who are currently skeptical?
  • People who are ?reporting negatively? and making ?negative accusations? on the ballpark and its funding.
  • ?Those who have attacked us.?
  • People who are ?attacking the County?s method of financing? for the ballpark;
  • ?columnists? who have ?decried? the trade;
  • ?We? meaning the team, for not communicating well with the fans. This is a superficial stab at responsibility, but the tone and placement of it is clearly that of a person who thinks they?re always right saying ?I guess I?m not being clear, because you still don?t understand that I am right.? If Loria did want to take responsibility for the poor?communication?he would mention the fact that he has given no interviews and made no statements at all since last season ended and until this letter was published. He has also apparently forbidden team officials from talking to the media too. Yes, Jeff, ?we? could do better with communication.
  • He would, however, like to remind us that he helped bring the 2003 World Series championship to Miami. I guess when the team plays poorly it?s on the roster, when they don?t it?s on him.

Give Loria this much credit: he?s honest. He does not believe he is in anyway responsible for what?s happened to this team, so he will not pretend to be responsible or sorry for it. ?I suppose in some strange, awful world there is something noble to that. Problem is, no one besides him believes it, so I don?t think the letter is going to do a thing for him or the team.

Source: http://hardballtalk.nbcsports.com/2013/02/25/shorter-version-of-jeff-lorias-letter-to-fans-its-everyones-fault-but-mine/related/

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Sexy Channing Tatum Inspires a Sexy Jamie Foxx Song

Here's what we learned following the Oscars: Jamie Foxx wants to Channing all over your Tatum.

Source: http://www.ivillage.com/jamie-foxx-sings-channing-tatum/1-a-523764?dst=iv%3AiVillage%3Ajamie-foxx-sings-channing-tatum-523764

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Friday, February 22, 2013

TV comic set to win seats in Italian general election

Feb. 21, 2013 ? It's not only in the US that actors are crossing over into politics. A recent publication in South European Society and Politicssuggests why comedian Beppe Grillo's Five Star Movement may win a certain number of seats in parliament at Italy's upcoming general elections.

A comedian with a rather particular background regarding his relationship with politics and television, Grillo is one of the figures most active in giving voice to the anti-political sentiment making a deep impact on the current orientation of Italian citizens.

Also interesting (and controversial) is his role within the MoVimento: he is the inspiration and mouthpiece of participation from the bottom up, but, at the same time, he also exercises a total control over the Movement's strategic choices.

This article tries to explain what the Five Star Movement is today: what organisational model it propounds, what challenges it poses for the system, as well as internal challenges. The general aim of this work is to shed light on the main characteristics of the Five Star Movement, and to see whether they can be read from a perspective of continuity -- or change.

Could this controversial comic end up being a major influencer in Italian politics?

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Story Source:

The above story is reprinted from materials provided by Taylor & Francis, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Fabio Bordignon & Luigi Ceccarini. Five Stars and a Cricket. Beppe Grillo Shakes Italian Politics. South European Society and Politics, 2013 DOI: 10.1080/13608746.2013.775720

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/mind_brain/consumer_behavior/~3/icWHjzU0cK4/130221091858.htm

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Taylor Swift BRIT Awards Performance: Watch, Try Not to Drool Now!

Source: http://www.thehollywoodgossip.com/2013/02/taylor-swift-brit-awards-performance-watch-try-not-to-drool-now/

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Research and Markets: Ford Motor Company- SWOT Framework Analysis 2013

DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/p89lq2/ford_motor) has announced the addition of the "Ford Motor Company- SWOT Framework Analysis" company profile to their offering.

SWOT Analysis, is a strategic planning tool used to evaluate the Strengths, Weaknesses, Opportunities, and Threats involved in a project or in a business venture. It involves specifying the objective of the business venture or project and identifying the internal and external factors that are favorable and unfavorable to achieving that objective.

The aim of any SWOT analysis is to identify the key internal and external factors that are important to achieving the objective. SWOT analysis groups key pieces of information into two main categories:

Internal factors - The strengths and weaknesses internal to the organization.

External factors - The opportunities and threats presented by the external environment.

The internal factors may be viewed as strengths or weaknesses depending upon their impact on the organization's objectives. What may represent strengths with respect to one objective may be weaknesses for another objective. The factors may include all of the 4P's; as well as personnel, finance, manufacturing capabilities, and so on. The external factors may include macroeconomic matters, technological change, legislation, and socio-cultural changes, as well as changes in the marketplace or competitive position. The results are often presented in the form of a matrix.

The report is also available in other formats. Please contact us for further information.

Key Topics Covered:

A. Executive Summary

B. A Brief Profile of the Company

C. SWOT Framework Analysis

C.1 Strengths to Build Upon

C.2 Weaknesses to Overcome

C.3 Opportunities to Exploit

C.4 Threats to Overcome

D. Glossary of Terms

For more information visit http://www.researchandmarkets.com/research/p89lq2/ford_motor

Source: http://feeds.businesswire.com/click.phdo?i=63b10102060bd89345a04981bcdc12ea

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Early-voting proposal raises constitutional questions (Star Tribune)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/286280616?client_source=feed&format=rss

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Thursday, February 21, 2013

Limit Major Decisions to Three People to Avoid Wasting Time

Limit Major Decisions to Three People to Avoid Wasting TimeCollaboration is great, but sometimes collaboration can devolve into useless debate that doesn't get you anywhere. The Globe and Mail recommend limiting those big decisions to three people or less.

The fewer people are involved, the less time you'll end up wasting:

Use the rule of three. Keep major decisions to three or fewer people. The more people involved the longer it takes to come to a consensus. Small teams coordinate and make decisions, while big ones quibble and form committees.

Similarly, they say meetings can be toxic to productivity, particularly if you do a bad job of sticking to the meeting's agenda. You don't want to undermine your coworkers by making every decision without them, but sometimes, things need to be decided quickly in order to keep productive and move forward. It's up to you to decide when that is. Hit the link for 10 more productivity tips for working with teams.

Ten ways to increase employee productivity | The Globe and Mail via Reddit

Photo by Office Now.

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/jT8afU0eRyo/limit-major-decisions-to-three-or-fewer-people-to-avoid-wasted-time

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Migratory behavior of oceanic whitetip sharks revealed

Feb. 20, 2013 ? As the nations of the world prepare to vote on measures to restrict international trade in endangered sharks in early March, a team of researchers has found that one of these species -- the oceanic whitetip shark -- regularly crosses international boundaries. Efforts by individual nations to protect this declining apex predator within their own maritime borders may therefore need to be nested within broader international conservation measures.

The research team, which included researchers from Microwave Telemetry, Inc., the Cape Eleuthera Institute, and the Institute for Ocean Conservation Science at Stony Brook University, attached pop-up satellite archival tags to one male and 10 female mature oceanic whitetip sharks off Cat Island in The Bahamas in May 2011, and monitored the sharks for varying intervals up to 245 days. The tags recorded depth, temperature, and location for pre-programmed periods of time. At the end of the time period, the tags self-detached from the sharks, and reported the data to orbiting satellites.

Their findings, published online February 20 in the journal PLOS ONE, show that some of these sharks roamed nearly 2,000 kilometers from the spot where they were caught, but all individuals returned to The Bahamas within a few months.

"While the oceanic whitetip shark is one of the most severely overexploited shark species, it is also among the least studied because it lives much of its life far from land in the open ocean," said Lucy Howey-Jordan, scientific liaison for Microwave Telemetry, Inc. and lead author. "Before this study and our ongoing research, very few of these sharks had been fitted with satellite tags, and the data we obtained will help establish new conservation measures."

All the tags, except the one attached to the male shark, reported data. Of the eight tagged oceanic whitetip sharks tracked for more than 31 days, three stayed within or very near The Bahamas Exclusive Economic Zone (EEZ) for their entire tracking period. The other five sharks, after an approximate 30-day period of residency within 500 kilometers of the tagging area, made long-distance movements outside of the EEZ, with one traveling as far as Bermuda. The fact that all these tagged mature female sharks returned to The Bahamas provides the first evidence of return-migration in this species. Additional findings that were surprising to the scientists included the sharks spending an average of 68 percent of the monitored time in Bahamian waters, and that these sharks, normally found near the ocean's surface, made dives of approximately 1,000 meters, possibly related to feeding behavior.

"Although these sharks are relatively safe from fishing in Bahamian waters, our study shows their long-range roaming takes them across the boundaries of different countries and into the high seas where they still encounter fishing gear set for other species," said Dr. Demian Chapman, an assistant professor in the School of Marine and Atmospheric Sciences and assistant director of science at the Institute for Ocean Conservation at Stony Brook University. "If we want to continue to see these animals in our oceans, fishing nations will have to work together to protect this species, and monitoring of trade and enforcement measures will need to be coordinated on an international level."

Once considered among the most abundant apex predators on Earth, overfishing has caused huge declines in oceanic whitetip sharks, and the species is listed as "Critically Endangered" in the Northwest Atlantic and Western Central Atlantic, and "Vulnerable" globally by the International Union for the Conservation of Nature. The fins of these sharks can be sold for $90 per kilogram because of the high demand for their use in shark fin soup, a delicacy in Chinese culture. There is growing international interest in improving the conservation of these sharks, including a proposal to list this species in Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES), which will be considered at its upcoming Conference of Parties meeting in Bangkok, Thailand, March 3-14 of this year.

World renowned for its healthy shark populations and proactive conservation stance, The Bahamas is one of the few places left in the world where this open-ocean species can be found in relatively large numbers. In July 2011, during the timeframe of this study, The Bahamas banned all commercial fishing of sharks throughout the 630,000 square kilometers of surrounding ocean waters. The sharks now benefit from this protection, and the shark diving industry, a major contributor to the Bahamian economy, benefits from their presence in surrounding waters. Additionally, recent studies have shown ecosystem health is dependant, in part, on the presence of apex predators like sharks.

"The Bahamian government had the foresight to protect these and other species of sharks within their waters, starting with the longline fishing ban in early 90s, and culminating with the more recent shark sanctuary initiative," said Edd Brooks, program manager of the Shark Research and Conservation Program at the Cape Eleuthera Institute. "This level of protection is vital for the continued existence of these important apex predators, and I hope that the example set by The Bahamas will encourage other nations to follow suit."

This research was funded by Microwave Telemetry, Inc., the Cape Eleuthera Foundation, The Pew Charitable Trusts, and the Roe Foundation.

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Story Source:

The above story is reprinted from materials provided by Stony Brook University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Lucy A. Howey-Jordan, Edward J. Brooks, Debra L. Abercrombie, Lance K. B. Jordan, Annabelle Brooks, Sean Williams, Emily Gospodarczyk, Demian D. Chapman. Complex Movements, Philopatry and Expanded Depth Range of a Severely Threatened Pelagic Shark, the Oceanic Whitetip (Carcharhinus longimanus) in the Western North Atlantic. PLoS ONE, 2013; 8 (2): e56588 DOI: 10.1371/journal.pone.0056588

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/GdLLZy8u3tQ/130220184721.htm

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Orleans Parish School Board president fails to win support for controversial moves

In the first full Orleans Parish School Board meeting of 2013, new President Ira Thomas tried to exercise his power on several fronts. In the end, though, all of his controversial moves were blocked.

Thomas filed an agenda item to nullify and renegotiate interim Superintendent Stan Smith's contract; instead, board members voted to review and then probably ratify that contract. Second, his attempt to void the contract of Deputy Superintendent for Charter Schools Kathleen Padian died when no other board member would support it. Finally, even though Thomas blocked a key tax-credit item from being added to the agenda, three board members went through the necessary procedure to get a special meeting called to address that issue Thursday.

Cynthia Cade, who was Thomas' closest ally on the school board in recent years, was out of town and unable to come to his aid.

Thomas joined the board in 2009 and won re-election in November. He represents eastern New Orleans and works as the police chief for Southern University at New Orleans. In January, the board elected him president unanimously in spite of several members' disagreement behind the scenes.?

Before Hurricane Katrina, Thomas was the head of security for the school board. He lost that job and sued the board for wrongful termination. Board attorney Ed Morris filed to get the suit dismissed last year after three years passed with no action on it.

Although Thomas objected to Padian's and Smith's appointments in May 2012 and has berated them at meetings, his proposals to nullify their contracts came as a surprise, added to the agenda at the last minute Monday evening.

Morris said he thought both contracts were invalid. In Padian's case, he said, the agenda item promoting her to deputy superintendent last year did not explicitly direct the board's staff to draw up a contract for her. Therefore, Morris said, the full board had never approved the contract the board's president at the time signed, rendering it invalid.

The issue with Smith's contract is that the board didn't OK all of its terms and conditions. The board set Smith's salary as interim superintendent but did not specify that when a permanent superintendent was hired Smith would return to his former position as chief financial officer, with a higher salary but no official car. Those financial terms should have gone back to the full board for approval, Morris said.

Board member Seth Bloom, a lawyer and one of those critical of Morris' arguments, asked why the attorney had not raised an objection at the time. "How did it get through (you) if it wasn't legal?" he asked.

Bloom questioned why the board couldn't simply fix any problems, and he filed a substitute motion to have the board look at Smith's contract, amend it if needed and then ratify it at a future meeting. That won the day over Thomas' more extreme measure to nullify and renegotiate the contract. Board Vice President Leslie Ellison and members Woody Koppel, Nolan Marshall Jr. and Sarah Newell Usdin voted in favor of Bloom's motion. Thomas abstained and Cade was absent.

On Padian's contract, Marshall attempted a compromise motion that would have voided her contract but then required Thomas, Ellison and Morris to negotiate a new one. That failed for lack of a majority, with Bloom, Koppel and Usdin voting against it. Then no one offered a motion to vote on Thomas' original item, rendering it dead. Thomas fumed at that, saying the board was sanctioning an illegal contract.

Former School Board President Thomas Robichaux, also a lawyer, said earlier Tuesday that the contract negotiations and signings for Padian and Smith had followed standard board procedure.

Padian's contract was discussed in a lengthy executive session -- a move that Caroline Roemer Shirley, head of the Louisiana Association of Public Charter Schools, said was illegal. The board did not let her speak further because she had submitted her "public comment" card too late.

Under the law, boards may discuss a matter behind closed doors if it's a personnel issue or if the board has received a "formal written demand" that threatens a lawsuit or implies a threat to sue, Louisiana Department of Education lawyer Joan Hunt said Tuesday. Padian told reporters she had not said or written anything indicating she might sue the board.

For personnel issues, Shirley said in an interview, the board is required to give the person to be discussed 24 hours' written notice and the option to have the matter discussed in open session instead.

Thomas also stood alone on the question of whether the board should approve about $2 million in tax credits for the new Wheatley School in Treme. The deal is set to close in the next 14 to 21 days -- if the OPSB signs the last papers this week. The major issue it needs to take care of is reauthorizing a corporation to receive the tax credits. The previous board created that corporation in the fall, but the decision has to be redone with the new board membership.

Usdin, Recovery School District Superintendent Patrick Dobard and representatives of several business and school reform groups argued that failing to check the final box on the project would not only take money away from kids but also embarrass the city.

"It will send an unfortunate message to investors nationwide" to stay away from New Orleans schools "because we cannot work together, OPSB and RSD," Dobard said.

Adding an item to the agenda at the meeting must be done by unanimous vote. Thomas cast the sole vote against adding the tax-credit item. He said he didn't understand why the board was being asked to allocate $22 million in order to get $2 million in credits. Usdin said that could be discussed if the item went on the agenda.

Despite Thomas' objections, the matter will be discussed Thursday instead. Usdin, Koppel and Bloom submitted a request for a special meeting; by board policy, if three members request a special meeting, it must be held.

The board approved new committee assignments with relatively little dissension. Usdin will chair the accountability committee, Ellison budget/finance, Bloom legal/legislative, Cade policy and Marshall property. Marshall will also chair the school building master plan oversight committee, which is a joint endeavor of the RSD and OPSB.

Source: http://www.nola.com/education/index.ssf/2013/02/orleans_parish_school_board_pr_2.html

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Tonight: 'Mad About Oscar,' 'Modern Family,' 'Dangerous Persuasions'

David Faustino, center, visits Julie Bowen and Ty Burrell on 'Modern Family.' Photo credit: Peter 'Hopper' Stone/ABC

If you need a refresher for Sunday?s Academy Awards, ABC will offer ?Mad About Oscar With Katie Couric.? The special ?20/20,? at 10 p.m. Wednesday, promises to replay?highlights from Oscar history.?Those should include David Niven and the streaker, Sally Field?s ?you like me? speech and Cher in her outlandish gown. The special?will feature?Field, Denzel Washington, Jennifer Lawrence and Bradley Cooper, all nominees this year.

Also this night:

David Faustino of ?Married ? With Children? visits ?Modern Family? at 9 on ABC.?The Emmy-winning sitcom stars Faustino?s former?TV dad, Ed O?Neill.

On ?The Middle,? at 8 on ABC, Frankie (Patricia Heaton) prepares to watch the Oscars. But she?s worried about a bus trip for Brick.

?Criminal Minds? was preempted last week for the ?Survivor? season premiere. The CBS crime drama is back at 9. CBS warns that a stalker ?inches closer in his pursuit of the team.?

CBS will follow that harrowing development with more bad news on ?CSI? at 10. Sara (Jorja Fox) becomes the lead suspect in an investigation, and CBS adds, ?her separation from Grissom begins to take a toll.?

Ten of the female hopefuls perform on ?American Idol? at 8 on Fox. Only five will?remain in the contest when the?singing ends tonight.

Investigation Discovery turns to a Central Florida crime in??Dangerous Persuasions? at 10. The program charts the story of? Mary Rich, who now lives in The Villages. She and her children share the chilling details about Ronald Larrinaga, who was a self-styled missionary at their? church. He persuaded Mary?s family to move in with his family in Palm Bay. Larrinaga was later convicted of 42 counts of physical and sexual abuse and sentenced to 180 years in prison.

Because this is February sweeps, the schedule is packed with new episodes, including ?Arrow? at 8 on The CW and ?Chicago Fire? at 10 on NBC. Enjoy because reruns are just around the corner.

Source: http://blogs.orlandosentinel.com/entertainment_tv_tvblog/2013/02/tonight-mad-about-oscar-modern-family-dangerous-persuasions.html

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Tuesday, February 19, 2013

Which Dumb Little Everyday Technology Do You Wish Was Better?

Two things about today practically guaranteed a bad day for me: it was raining and my nails were long. Why are these two things a harbinger of annoyance? Because I hate the little everyday 'technology' that's involved in solving their problems. Boo hoo me, right? More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/JvK-epvr31U/which-dumb-little-everyday-technology-do-you-wish-was-better

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Bridgewater business owner has big plans, including roadside stand and eventually mini golf

Steven Prisco has big plans for this small town. He has ever since 2006, when he and his wife Nancy bought land off Route 18 where Prisco?s Market & Deli now stands.

Last week, those plans edged forward as Prisco began to build out the next stage of his mom-and-pop market.

Construction has started, he said, on a roadside stand set to open in April, which the business?s Facebook fans have already christened as Prisco?s Country Creamery.

?I think we?re really going to hit a home run with this,? Prisco said Friday.

The town?s building inspector signed off on the 1,200-square-foot project last month.

Prisco describes the idea as a ?game-changer? for his business and a win-win for Bridgewater, expected to create 15 to 20 more jobs in the community.

The stand will set closer to the roadway and act as a mini Prisco?s Market & Deli, serving people in need of a quick lunch ? everything from hot dogs to meatballs and fried clams. And of course, ice cream, bought wholesale from Puritan of Roslindale. Customers will be asked to pick the flavors.

?I?m shooting to have one of the best roadside stands in New England,? he said.

Around the small snack shack will sit eight picnic tables, and plenty of room for parking, said Prisco, who hopes the stand will also draw customers to the market set back further down Romney Road.

He plans to run a 10-person golf cart as a shuttle service between the two.

Nick Palmeiri, president of the Bridgewater business association, said the addition could be a boon for Bridgewater, bringing people in who might also shop at other stores in town.

?We, as a community, for years talked about the fact that we need to build our business base,? Palmeiri said Friday. ?Any business that you can bring into town, any quality business, is an asset to us, plain and simple.?

Next up on Prisco?s agenda? A mini golf course, but that could be a few years down the road.

The big plan, is to become a family-friendly destination and a mainstay in the community.

?We want a place where people from the local area, and 25 miles around, they have a place to come that?s clean fun and affordable,? he said. ?That?s my goal.?

Amy Carboneau may be reached at acarboneau@enterprisenews.com, or follow her on Twitter @amycarboneau.

READ MORE about this issue.

Source: http://www.enterprisenews.com/features/x694774570/Bridgewater-business-owner-has-big-plans-including-roadside-stand-and-eventually-mini-golf

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Rain, cold weather returns to Bay Area

Another winter storm is approaching California, where it's expected to bring freezing temperature, thunder, rain and snow as low as 1500 feet.

The National Weather Service said the cold weather system from the Gulf of Alaska was expected to reach the Bay Area late Monday and rain was forecast for Tuesday morning's commute.

Dark clouds started rolling across the Bay Area late Monday afternoon, and the menacing-looking sky obliterated the bright sunshine that many enjoyed the last few weeks.

"Oh, man it was wonderful. It was just great. I was grateful because I had a lot of outside work to do," said Joe Munch of Mendocino County.

An unusually wet November and December gave Bay Area water agencies a strong start to the rainy season.

At Lake Lagunitas in Fairfax, the water level is high enough that some came over of the spillway.

Marin County relies almost entirely on rainfall to replenish its water supply and despite the third driest January on record, Marin's reservoirs are at 98 percent of capacity.

East Bay Municipal Utilities District gets 90 percent of its water from Sierra sno pack and right now its reservoirs are at 81 percent of capacity.

In the South Bay, things are not looking so bright for the Santa Clara Valley Water District where the reservoirs are just 50 percent full.

The San Francisco Public Utilities Commission was unavailable on the President?s Day holiday to provide information on the Hetch Hetchy Reservoir which supplies the city and much of the peninsula.

But a United States Geological Survey website shows that as of Monday, Hetch Hetchy is still almost full.

?In Northern California, the heaviest snow was expected to drop Tuesday, bringing up to 10 inches above 3000 feet and 2 to 4 inches in the foothills above 2000 feet.

The storm was expected to move out of the state by Wednesday.

Source: http://www.ktvu.com/news/news/local/rain-cold-weather-returns-bay-area/nWSKF/

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DealAngel Launching API To Let Other Sites Build Hotel Pricing Intelligence Into Their Wares

152781v4-max-250x250DealAngel, the site that lets you search for hotels and compare prices based on their historic and broader market value to ensure you really are getting a good deal, has launched a private beta of its API -- essentially adding a B2B element to its otherwise consumer-facing offering. It's a move that makes quite a bit of sense, too, potentially opening up DealAngel's data to additional use-cases and giving the startup an alternative revenue stream. The API should go fully public by April, while Social trip planner Gogobot is the first to add such integration. It also comes at a time when the San Francisco/Prague-based company is ramping up its European expansion: DealAngel is now able to apply its hotel pricing intelligence to hotels in the UK, Germany, and over two dozen "strategic" cities elsewhere in Europe such as Amsterdam, Paris, Barcelona, and Prague, in addition to major cities in Russia and Israel. It also targets much of North America.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/HJac5qMf-l4/

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Monday, February 18, 2013

George P. Bush to speak at NM GOP event

ALBUQUERQUE, N.M. --?

The nephew of former President George W. Bush is scheduled to address Republican Party activists in New Mexico.

Republican Party of New Mexico Chairman John Billingsley announced that George P. Bush will be the keynote speaker at RPNM's annual Lincoln Day Dinner on March 23.

The younger Bush is the son of former Florida Gov. Jeb Bush and wife, Columba, a naturalized U.S. citizen from Mexico.

Bush told Texas Republicans last week that conservative Republicans could compete for Latino voters by emphasizing energy production and education and still remaining true to their core values.

He recently announced that he planned to run for statewide office in Texas in 2014.

Source: http://www.fortmilltimes.com/2013/02/17/2502092/george-p-bush-to-speak-at-nm-gop.html

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Golf-Pacesetting Haas sticks to successful Riviera recipe

By Mark Lamport-Stokes

PACIFIC PALISADES, California | Sun Feb 17, 2013 1:11am GMT

PACIFIC PALISADES, California Feb 16 (Reuters) - It took Bill Haas a long time to work out how to play Riviera Country Club effectively at the Northern Trust Open, but for the past two years he has certainly come up with the right formula.

Twelve months ago, he edged out fellow Americans Phil Mickelson and Keegan Bradley to win the prestigious title at the second extra hole and this week he will take a commanding three-shot lead into Sunday's final round.

Haas has always loved the challenge of Riviera, one of the classic layouts on the PGA Tour, but had finished no better than joint 22nd in his first five starts at the event, including missed cuts in 2009 and 2010.

"Even before last year when I did not have the best of records here, it was certainly a week that I penciled in on the schedule if I could get in and play here," Haas told reporters after firing a seven-under-par 64 in Saturday's third round.

"It's fun to play. I like everything about Riviera ... the golf course, the grass, just how it's an old-school style golf course.

"Walking in the locker room, seeing the pictures of all those champions on the wall, it's just got a great feel of it about it."

Conditions were extremely tough on Saturday with the course running fast and firm under a dazzling sun but Haas stayed patient and made the most of his opportunities when they came to post a 12-under total of 201.

"Temperature-wise, it was fabulous but with that some of the fairways are really running out, the greens are difficult to hit and it's getting firmer and firmer," the 2011 FedExCup champion said after mixing five birdies with an eagle at the 10th.

"Just because it's playing shorter doesn't mean it's necessarily playing easier. Today I was able to save a shot here and there, make a couple of nice par saves. I hit some really nice chips from around the greens."

BIG NAMES

Haas, a four-times winner on the PGA Tour, has several big names in hot pursuit with U.S. Open champion Webb Simpson and 2011 Masters winner Charl Schwartzel three strokes adrift, and world number three Luke Donald a further shot back.

"It's very difficult in this game to just pull away from the rest of the field," Haas said of the task facing him in the final round. "You've only seen a few guys ever really do that ... guys like Jack Nicklaus, Tiger Woods, Phil Mickelson.

"I've just got to try to stay in the moment, don't let my emotions get the best of me, try to get off to a good start.

"The guys behind me are going to make birdies and will certainly get closer at the top, so I've just got to try to hang in there and give myself a chance on the back nine."

The 30-year-old American is experienced enough to know that good form can never be taken for granted.

"Every day is a new day and you're always working," said Haas, whose distinguished golfing lineage includes his father Jay, a multiple winner on the PGA and Champions tours, and his great uncle Bob Goalby, best known for winning the 1968 Masters.

"My dad always said, 'When you're playing well, you're not far off from playing poorly; and when you're playing poorly, you're not far off from playing well.'

"There's just such a fine detail in your swing that can change daily, so you just always keep working on it." (Reporting by Mark Lamport-Stokes; Editing by Frank Pingue)

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Source: http://www.thespainforum.com/f234/golf-pacesetting-haas-sticks-successful-riviera-recipe-413462/

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Sunday, February 17, 2013

Breakthrough architecture for quantum computers proposed

Feb. 15, 2013 ? A team of researchers at the University of Waterloo's Institute for Quantum Computing has proposed a new computational model that may become the architecture for a scalable quantum computer.

In a paper to be published in the journal Science this week, the research team of IQC Associate Professor Andrew Childs, post-doctoral fellow David Gosset and PhD student Zak Webb proposes using multi-particle quantum walks for universal computation. In a multi-particle quantum walk, particles live on the vertices of a graph and can move between vertices joined by an edge. Furthermore, nearby particles can interact with each other.

Traditionally, a quantum algorithm is implemented on a register of qubits by actively manipulating the qubits according to a set of desired operations. In this new model, a desired quantum algorithm can be implemented by letting the qubits "quantum walk" on an appropriately chosen graph, without having to control the qubits. The process is analogous to a billiard-ball computer where classical logic gates are performed using collisions.

Many previous quantum-walk experiments have not been scalable. But this new model proposed by Childs and his team identifies the requirements to implement quantum walks so they have the potential for significant quantum speedup, paving the way for scalable future experiments. The model could be naturally realized in a variety of systems, including photons with interactions mediated by superconducting circuits.

Quantum walk-based computing is particularly promising because of its universality. "In principle we can cast any quantum algorithm into this model," says Childs. In future work, Childs and his team are interested in applying the model to develop new quantum algorithms and to study problems in quantum computational complexity.

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Journal Reference:

  1. A. M. Childs, D. Gosset, Z. Webb. Universal Computation by Multiparticle Quantum Walk. Science, 2013; 339 (6121): 791 DOI: 10.1126/science.1229957

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/computers_math/information_technology/~3/xjO4rm2hZsM/130217084916.htm

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Coach's criticism ignites Duquesne's Marhold

After a 22-point blowout loss Feb. 5 against George Washington, Duquesne coach Jim Ferry blasted his team's lack of effort, called into question the leadership of some upperclassmen and called out senior post player Andre Marhold, saying "he has given us nothing for quite a long time."

It was that last bit -- calling out a player publicly -- that got some people's attention because coaches ordinarily don't go that route. But Ferry has been a straight shooter since he arrived and was being honest about why Marhold was no longer a starter.

Marhold, however, had no problem with what Ferry said because he knew he wasn't getting the job done and needed a wake-up call.

"I was OK with it because I am not good at communicating things often and, sometimes, I probably don't always hear what people are saying," Marhold said, then laughed. "But me sitting on the bench and hearing my coach say I am not helping the team, well, that's a good way to get my attention."

Clearly, Ferry's motivational tactic worked because Marhold had an excellent game in the loss against Xavier last Saturday and earned his way back into the starting lineup for the Dukes stunning, 84-83 win Thursday night at Temple.

In fact, since Ferry called him out, Marhold has been the Dukes' best player. He scored nine points and grabbed 10 rebounds against the Musketeers and posted 15 points and 15 rebounds against the Owls.

  • Matchup: Duquesne (8-16, 1-9 Atlantic 10) vs. Rhode Island (7-16, 2-9), 7 p.m. today, Palumbo Center.

  • Radio: WPGB-FM (104.7).

  • Duquesne: Ended an 11-game losing streak Thursday with 84-83 win at Temple. ... Andre Marhold has scored 24 points and grabbed 25 rebounds in past two games. ... Marhold started against Temple after being a reserve for several weeks. ... Average 12.6 turnovers per game.

  • Rhode Island: Ended 6-game losing streak with a 75-72 win Wednesday against Dayton. ... Leading scorer is Xavier Munford (17.5 ppg). ... Leads series with Duquesne, 28-24, but is 11-12 in games in Pittsburgh. ... Won a thriller, 77-76, in 2011 in last trip here.

  • Hidden stat: Duquesne has lost five home games in a row; Rhode Island has lost three consecutive road games.

Marhold also had three blocked shots in the waning moments of the Temple game, and they were huge as the Dukes won by one point. Every possession was crucial.

He said that as soon as he heard Ferry's comments he knew his coach was right and decided to make the necessary changes to his attitude and work habits to ensure that he could finish his senior year the right way and help his team win some games down the stretch.

"I just used Coach's comments as motivation, decided I needed to take a look in the mirror and see what it was that I could do better," Marhold said. "I just knew that I needed to change, go back to being that leader, getting our guys hyped and ready, working hard at practice, doing everything in my power to make changes so that I can become not just a better player but also a better person.

"I feel like I know what he is talking about, he wants us not just to play hard but to make plays as well. My mentality has changed. Now, I am thinking in terms of making plays.

"Really, it was on me, I know that, and I just want to make sure that I keep working hard and really improving and being a leader the rest of the way here."

Marhold will start tonight when Duquesne (8-16, 1-8 Atlantic 10) plays host to Rhode Island (7-16, 2-8). He said he plans on being a starter the rest of the way.

"I need to keep this going," he said. "Just working hard and being a leader and helping us win games, that's where my focus needs to be."

The win against Temple broke an 11-game losing streak, but Marhold said that is behind the Dukes, who are now trying to mount a winning streak.

"We experienced a big win before -- against West Virginia -- then got all happy and came out the next game flat and got blown out of the gym by team we could beat [Robert Morris], so we know what that is like and aren't going to do that again," Marhold said. "Guys got a taste of winning and want more, and there were a lot of guys in [Friday] early watching film, working out and getting focused on our next game.

"I know we are going to come out ready to play and play as hard on defense as we did against Temple and, if we do that and rebound, we will have a great chance to win."

Source: http://www.post-gazette.com/stories/sports/duquesne/coachs-criticism-ignites-duquesnes-marhold-675600

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In a first, Obama plays golf with Tiger Woods

PALM CITY, Florida (Reuters) - President Barack Obama had a chance to see how golf is played at the highest level on Sunday, teeing off with Tiger Woods, the world's No. 2 golfer.

Obama, an avid weekend golfer, and Woods, who won his 75th title last month, played together for the first time at the Floridian Yacht and Golf Club.

Less than a month after starting his second term, Obama is on a three-day golf getaway in Florida, while his wife, Michelle, and their daughters, Malia and Sasha, are skiing in Colorado. On Saturday he received instructional tips from Woods' former swing coach, Butch Harmon.

White House spokesman Josh Earnest said Obama and Woods were joined on the course by U.S. Trade Representative Ron Kirk and Jim Crane, the resort owner who also owns the Houston Astros baseball team.

Tim Rosaforte, a Golf Channel analyst and Golf Digest writer, broke the news, tweeting that Woods holed out from a greenside sand bunker on the first hole.

"Historic day in golf. Their first round," Rosaforte said.

There was no word on how Obama played.

The White House did not permit the media pool onto the grounds of the resort in order to record any part of the Woods-Obama round.

Woods, who usually steers clear of politics, is the top-ranked American golfer and second in the world. He lives about an hour south of the Floridian club in Jupiter, Florida.

Woods has been rebuilding his image after extramarital affairs came to light in 2009 that led to his divorce.

Like many of his predecessors, Obama has escaped the pressures of the Oval Office by taking to the golf course. He has played more than 100 rounds of golf as president and typically tees it up with a group of close-knit friends.

(Reporting By Steve Holland; Editing by Bill Trott)

Source: http://news.yahoo.com/obama-buddies-golf-weekend-floridas-atlantic-coast-012329504--golf.html

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WSJ: Sony will use Gaikai streaming tech to play PS3 games on the PS4

We're just a few days away from Sony's February 20th "see the future of" PlayStation event where we expect to see the next edition of its home console, and the rumor mill is buzzing. The latest one tonight comes from the Wall Street Journal, with a report that connects Sony's $380 million purchase of cloud gaming service Gaikai last year with a method to provide backwards compatibility on the PlayStation 4. The WSJ reports Sony has been "investing heavily" in preparing Gaikai for an influx of PS4-equipped gamers, while also developing better cameras for its Move and the DualShock+touchpad controllers we've seen recently.

What's not revealed however, is any potential pricing plan, or whether cloud games will work users existing cloud saves. While buying fully digital copies of games we already own is less than appealing, if Sony can implement something like the abandoned UMD-to-PSP Go "good will" plan, then there may be benefits for all.

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Source: Wall Street Journal

Source: http://www.engadget.com/2013/02/15/sony-ps4-gaikai-streaming-rumor/

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Saturday, February 16, 2013

Why cells stick: Phenomenon extends longevity of bonds between cells

Friday, February 15, 2013

Research carried out by scientists at the Georgia Institute of Technology and The University of Manchester has revealed new insights into how cells stick to each other and to other bodily structures, an essential function in the formation of tissue structures and organs. It's thought that abnormalities in their ability to do so play an important role in a broad range of disorders, including cardiovascular disease and cancer.

The study's findings are outlined in the journal Molecular Cell and describe a surprising new aspect of cell adhesion involving the family of cell adhesion molecules known as integrins, which are found on the surfaces of most cells. The research uncovered a phenomenon termed "cyclic mechanical reinforcement," in which the length of time during which bonds exist is extended with repeated pulling and release between the integrins and ligands that are part of the extracellular matrix to which the cells attach.

Professor Martin Humphries, dean of the faculty of life sciences at the University of Manchester and one of the paper's co-authors, says the study suggests some new capabilities for cells: "This paper identifies a new kind of bond that is strengthened by cyclical applications of force, and which appears to be mediated by complex shape changes in integrin receptors. The findings also shed light on a possible mechanism used by cells to sense extracellular topography and to aggregate information through 'remembering' multiple interaction events."

The cyclic mechanical reinforcement allows force to prolong the lifetimes of bonds, demonstrating a mechanical regulation of receptor-ligand interactions and identifying a molecular mechanism for strengthening cell adhesion through cyclical forces.

"Many cell functions such as differentiation, growth and the expression of particular genes depend on cell interaction with the ligands of the intracellular matrix," said Cheng Zhu, a professor in the Coulter Department of Biomedical Engineering at Georgia Tech and Emory University and the study's corresponding author. "The cells respond to their environment, which includes many mechanical aspects. This study has extended our understanding of how connections are made and how mechanical forces regulate interactions."

The research was published online by the journal on February 14th. The work was supported by the National Institutes of Health (NIH) and the Wellcome Trust.

Cells of the body regulate adhesion in response to both internally- and externally-applied forces. This is particularly important to adhesion mediated by proteins such as integrins that connect the extracellular matrix to the cytoskeleton ? and provide cells with both mechanical anchorages and the means to initiate signaling.

Using delicate force measuring equipment, researchers in Zhu's lab and the laboratory of Andres Garcia ? a professor in the Woodruff School of Mechanical Engineering at Georgia Tech ? collaborated to study adhesion between integrin and fibronectin, a protein component of the extracellular matrix. What they found was that cyclic forces applied to the bond switch it from a short lived state ? with lifetimes of about one second ? to a long-lived state that can exist for more than a hundred seconds.

"Force can be very important in biology," said Zhu. "Force has direction, magnitude and duration, so in describing its effects on biological systems, you have to use a more complete language."

Zhu, Garcia and Georgia Tech graduate students Fang Kong, William Parks and David Dumbauld ? along with postdoctoral fellow Zenhai Li ? used two different mechanical techniques to study the strength of bonds between integrin and fibronectin. One technique measured the bond strengths in purified molecules, while the other studied the effects of them in their native cellular environment.

"We have very precise force transducers that allow us to measure force on the scale of pico-newtons," said Zhu. "We prepare the samples in such a way that we engage only one bond, then we control the application of force and observe what happens."

The researchers first used an atomic force microscope to bring the integrin molecule together with the fibronectin, then separate the two. Instruments measured the pico-newton forces required to separate the molecules, and found that the duration of the bonds increased with the repetition of the contacts.

The second technique, known as BFP, involved the use of a fibronectin-bearing glass bead attached to a red blood cell aspirated by a micropipette. Integrin expressed on the micropipette-aspirated cell was pressed into the bead, then pulled away over repeated cycles. Lifetime measurement confirmed that repeated pulling increased the longevity of the bonds.

The researchers studied two integrins, part of a family of 24 related molecules that operate in humans. In future work, they hope to determine whether or not the cyclic mechanical reinforcement they observed is a universal property of many cellular adhesion molecules.

The researchers also hope to explore how cells use this cyclic mechanical reinforcement. Because many disease processes result from abnormal cellular adhesion mechanisms, a better understanding could provide insights into how cardiovascular disease, cancer and immune system disorders operate.

"The findings of the paper have deep implications for our understanding of force-regulated signaling," added Humphries. "There is abundant biological evidence for profound effects of extracellular tensility and elasticity in controlling processes such as cancer cell proliferation and stem cell differentiation, but the mechanisms whereby this information is transduced across the outer cell membrane are unclear."

###

Georgia Institute of Technology: http://www.gatech.edu

Thanks to Georgia Institute of Technology for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126851/Why_cells_stick__Phenomenon_extends_longevity_of_bonds_between_cells

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Budget cut impact: Smaller Navy, fired teachers

What does smaller government look like? The budget standoff between President Barack Obama and congressional Republicans means Americans may soon find out, and the picture the Obama administration sketches is downright scary.

Cuts in the Navy's Pacific operations of one-third. Furloughed food inspectors forcing nationwide closures of meat and poultry plants. Ten thousand laid-off teachers. A $1 billion reduction in the relief fund for disaster victims. Less secure airline flights and longer waits on airport security screening lines. Reduced monitoring of air pollution, oil spills and hazardous waste.

All this and more because $85 billion in cuts across most federal programs will be automatically triggered March 1 unless Obama and Republicans do something that's eluded them for months: approve alternative savings.

A look at the fight over the so-called sequester, and what its impact could be:

?State of play: The cuts ? plus nearly $1 trillion more over the coming decade ? were enacted two years ago in hopes that their sheer ugliness would force the two sides to replace the reductions with a sweeping, bipartisan deficit-reduction deal. So far that's not happened.

The administration has repeatedly warned that the sequester must be avoided. White House budget office controller Daniel L. Werfel told Congress on Thursday that they would have "destructive consequences."

Though many lawmakers of both parties would like to find a way out, conservative Republicans have said they're willing to live with the reductions. House Speaker John Boehner, R-Ohio, told The Associated Press this week that "we're going to be stuck with it" until Obama proposes a solution that can pass the Democratic-led Senate.

?Overall impact: Administrations past and present always excel at threatening scenarios that make it appear that life as we know it will end. In this case, the law limits the flexibility government officials will have to protect favored programs, but Werfel wrote that the White House has instructed agencies to give priority to avoiding cuts that could "present risks to life, safety or health" and seek other ways to minimize harm to important government services.

The sequester law exempts Social Security, Medicaid, food stamps and Medicare recipients' benefits from cuts, but most programs are vulnerable.

The cuts were expected to mean reductions this year of 8 percent in defense and 5 percent in nondefense programs. But because lawmakers recently delayed the impact until March 1 ? meaning they will affect only the last seven months of the government's budget year ? the sequester will force deeper reductions of 13 percent for defense and 9 percent for other programs.

?Defense: The Defense Department announced last week that because of the cuts it is withdrawing one of its two aircraft carriers from the Persian Gulf region, but there's more coming.

The Navy's top officer, Adm. Jonathan Greenert, told Congress that because of the sequester and already planned long-range reductions, the Navy could not fully support counterterrorism operations in Somalia and Yemen. A letter the Pentagon sent to Congress this week says the military will protect operations for ongoing wars, but expects to curtail maintenance of aircraft and ships, reduce training and maintenance for some Army units and cut Air Force flying hours. There would probably be a freeze in hiring civilians, instead of the 1,500 to 2,000 new jobs monthly. Current civilian workers could be furloughed up to 22 days. And the military's Tricare health care system could lose $3 billion, threatening elective care for some military dependents and retirees.

?Homeland Security: Homeland Security Secretary Janet Napolitano wrote to Congress that there will be fewer border agents and fewer facilities for detained illegal immigrants. There would be reduced Coast Guard air and sea operations, furloughed Secret Service agents and weakened efforts to detect cyberthreats to computer networks. The Federal Emergency Management Agency's disaster relief fund would lose more than $1 billion. "We do not have the luxury of making significant reductions to our capabilities without placing our nation at risk," Napolitano wrote.

?Education: Education Secretary Arne Duncan told Congress that 70,000 Head Start pupils would be removed from the pre-kindergarten program, about 1 of every 13. Duncan warned those cuts would mean layoffs of 10,000 teachers and thousands of other staffers because of cuts in federal dollars that state and local governments use for schools. Cuts for programs for handicapped and other special needs students would threaten 7,200 teachers and aides, he said.

?Health: The National Institutes of Health would lose $1.6 billion, trimming research on cancer, drying up money for hundreds of other research projects and eliminating up 20,000 private research positions nationwide. Health departments would give 424,000 fewer tests for the AIDS virus this year. More than 373,000 seriously ill people may not receive needed mental health services.

?Transportation: The Federal Aviation Administration plans to furlough most of its 47,000 employees, including air traffic controllers, for an average of 11 days, with most furloughs probably over the summer. FAA Administrator Michael Huerta told employees in a letter this week that while the furloughs can be managed safely, "We might see travel delays and disruptions during the critical summer travel season."

?Environment: Cuts to the Environmental Protection Agency would jeopardize its ability to protect the public from oil spills, air pollution and hazardous waste, according a letter from Bob Perciasepe, who becomes interim head of the agency on Friday until a replacement is named. States would have to shut down some pollution monitors that determine if air is healthy to breathe. The popular color-coded air quality forecasting system that keeps schoolchildren and others inside on bad-air days would be curtailed or eliminated.

The EPA, which already inspects only a tiny fraction of facilities with the potential to spill oil, would do even less. New models of cars and trucks could be delayed from getting to dealership lots because the EPA couldn't quickly validate that they meet emissions standards.

?Internal Revenue Service: A Treasury Department letter to Congress said the IRS would review fewer tax returns, which "could result in billions of dollars in lost revenue." The agency offered no specifics but said each $1 spent on the IRS has meant at least $4 in additional revenue.

?Agriculture: The Agriculture Department says meat inspectors could be furloughed up to 15 days, shutting meatpacking plants intermittently and costing up to $10 billion in production losses and $400 million in lost wages. The Food and Drug Administration would conduct 2,100 fewer food facility inspections this year. About 600,000 low-income pregnant women and new mothers would lose food aid and nutrition education.

?FBI: FBI Director Robert Mueller wrote to Congress that sequestration would be the equivalent of cutting 2,285 employees, including 775 agents, through furloughs and a hiring freeze. Every FBI employee would be furloughed for 14 workdays.

? Interior Department: The department says it is preparing to reduce hours and services at all 398 national parks and might close up to 128 wildlife refuges. As much as $200 million in direct payments to states, mainly the West, could be eliminated. The cuts could force local governments to cut back on police and fire protection, schools, road maintenance and more.

?Labor: More than 3.8 million people jobless for six months or longer could see their unemployment benefits reduced by as much as 9.4 percent. Thousands of veterans would not receive job counseling. Fewer Occupational Safety and Health Administration inspectors could mean 1,200 fewer inspections of dangerous work sites. There would be fewer investigations into complaints workers are being denied minimum wage and overtime pay. About 1 million fewer people would get help finding or preparing for new jobs.

?NASA: Nearly $900 million in cuts would come from programs including money to help private companies build crew capsules to eventually send astronauts to the International Space Station, and to test new technologies for sending astronauts into deep space.

?Housing: The Department of Housing and Urban Development said about 125,000 households could lose benefits from the agency's Housing Choice Voucher program and risk becoming homeless. The vouchers are the federal government's major program to assist low-income families, the elderly and the disabled.

___

Associated Press writers Seth Borenstein, Dina Cappiello, Matthew Daly, Philip Elliott, Sam Hananel, Mary Clare Jalonick, Richard Lardner, Joan Lowy, Andrew Miga, Lauran Neergaard, Stephen Ohlemacher and Pete Yost contributed to this report.

Source: http://news.yahoo.com/budget-cut-impact-smaller-navy-fired-teachers-222234326.html

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Friday, February 15, 2013

Breakthrough in ovarian cancer: Selumetinib

Feb. 14, 2013 ? Researchers at The University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center in Phoenix have discovered that many women with low-grade serous carcinoma of the ovary or peritoneum have seen their tumors stabilize or shrink after taking a regular dose of the compound selumetinib.

The findings, published in the Feb. 14 edition of The Lancet Oncology, show that selumetinib targets a mutation in the MAPK pathway for patients with low-grade serous carcinoma, allowing for treatment on previously chemoresistant tumors.

"This is a potentially important breakthrough for the Gynecologic Oncology Group," said John Farley, MD, a gynecologic oncologist in the Division of Gynecologic Oncology and the Department of Obstetrics and Gynecology at the Creighton University School of Medicine at St. Joseph's Hospital and Medical Center, a Dignity Health Member.

The Gynecologic Oncology Group is a non-profit international organization with the purpose of promoting excellence in the quality and integrity of clinical and basic scientific research in the field of gynecologic malignancies.

Dr. Farley is part of the University of Arizona Cancer Center at St. Joseph's and is board certified in obstetrics and gynecology with a subspecialty certification in gynecologic oncology. He is a retired decorated Army colonel who completed a residency in obstetrics and gynecology and a fellowship in gynecologic oncology at Walter Reed Army Medical Center. He is the first author on this study.

This study was initially developed in 2007, with 52 patients enrolled for the Phase II clinical trial between December 2007 and November 2009. Patients were given 50 milligrams of selumetinib orally twice daily. Of those participants, eight had a measurable decrease in tumor size, seven had partial responses and 34 patients saw their tumors stabilize. The findings suggest that inhibitors of the MAPK pathway warrant further investigation in patients with low-grade ovarian cancer.

"There just aren't very good treatments for low-grade ovarian cancer, so this discovery opens up a lot of new exciting possibilities for us," Dr. Farley said. He added that Phase III of this trial is scheduled to begin in the next few weeks, with that trial to be the "definitive test" before the treatment becomes available to the general population.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/APNtHJ_f5IQ/130214194149.htm

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Cardinal Health to buy medical supplier AssuraMed for $2.07 billion

(Reuters) - U.S. drug wholesaler Cardinal Health Inc said it plans to acquire AssuraMed, a privately held direct-to-home medical supply distributor, for about $2.07 billion.

The acquisition will give Cardinal access to a new segment of the healthcare market that it believes will grow with the implementation of the Affordable Care Act (ACA), or Obamacare, as it is more commonly known.

The deal, financed with $1.3 billion in new senior unsecured notes and cash, is expected to close by early April.

Cardinal Health said the acquisition would add 2 cents to 3 cents per share to adjusted fiscal 2013 earnings if the deal closes in early April. It would add at least 18 cents per share to adjusted earnings in fiscal 2014.

AssuraMed will give Cardinal access to the growing number of Americans who are treated in home settings. The ACA is expected to accelerate this trend, George Barrett, chairman and chief executive, said in a telephone interview.

An aging population, more prevalent chronic diseases, and the need to keep treatment costs down are factors that will necessitate more home care in years to come, he said.

"We see this as the natural direction of care that's moving toward the home," Barrett said.

AssuraMed, with sales of about $1 billion in 2012, serves more than 1 million patients nationally with more than 30,000 products. It helps patients manage insulin infusion, diabetes testing, incontinence, tube feeding, wound care, tracheotomy and provides a host of other healthcare services.

AssuraMed operates through two separate businesses, Independence Medical and Edgepark Medical Supplies.

The market for direct-to-home medical supplies is currently fragmented and Cardinal is betting it can capitalize on it with this acquisition and its expertise in supply chain, logistics and technology.

Cardinal shares were up 82 cents, or 1.8 percent, to $46.26 in morning trading on the New York Stock Exchange.

(Reporting by Debra Sherman; Editing by Roshni Menon and Nick Zieminski)

Source: http://news.yahoo.com/cardinal-health-buy-medical-supplier-assuramed-2-07-125117585--finance.html

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How To Master LinkedIn In A Day - Internet Marketing Academy




February 14, 2013


daily calendarEspecially with all of the changes that have been rolled out in the past few months, LinkedIn has a large number of features. However, you do not need to learn all of them at once. Instead, to become a LinkedIn master, you need to learn the 20% of functions that will give you 80% of the benefit of using LinkedIn. You can easily learn those functions within one day by focusing on your company page.

Why you need a company page

Company pages let you communicate with fans and followers of your company and its products, recruit new talent, and collect and share testimonials and endorsements for your products and services. LinkedIn provides useful analytics regarding visitors, including what your visitors are most interested in learning more about, which lets you tailor your messages to appeal to these prospective customers.

Create a company page

To create a company page, navigate to http://www.linkedin.com/companies and click on ?Add a Company?. Enter the company name and an email from the company domain. Click on ?Edit Page? and assign admin authority to everyone in the company who is authorised to post changes to the company page, or else everyone from the company domain can update the page. Enter the details about your company, including a keyword rich summary in ?About Us?. Click on the ?Products & Services? tab and edit that page to list all of your company?s products and services, with the most important ones listed first. Be sure to include purchase links. If you have job openings in your company, click on the ?Careers? tab and edit that page as well.

Drive engagement with content

The first content to drive engagement is your cover image. Make it visually engaging and representative of your company, such as a scene of people using your product, rather than a company logo. Next, request reviews of your products and services from your existing customers. Have all of your company?s employees connect to the company page. Publish useful content about your company, products, and services that is targeted to specific customer and employee demographics, as well as important featured content available to everyone. Make sure that all content, whether on LinkedIn, on your website, or in other social media, contains buttons or links to allow people to become followers of the company page.

Drive leads with ads

LinkedIn ads allow you to send your message to the 175 million worldwide LinkedIn users. This number includes nearly 8 million business decision makers, more than 1 million small business owners, more than 4 million corporate executives, and 5 ? million IT and technology managers. LinkedIn ads allow you to target specific job titles and functions, industry, company size, seniority, age, or membership in particular LinkedIn groups. Use standard best practices for pay per click advertising such as split testing, using many targeted ads versus a few general ads, and appealing to people close to making a buying decision.

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Thanks!

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Sean

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Sean McPheat

Managing Director

The Internet Marketing Academy

http://www.internetmarketingacademy.com

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(Image: MorgueFile)


Posted in Social Media | Tagged pay per click, social media marketing, social networking |

Source: http://www.internetmarketingacademy.com/blog/how-to-master-linkedin-in-a-day/

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